For years, my nostrils have been blocked by hardened, stinking matter that bleeds when scraped away. Silver nitrate treatments provide only fleeting relief. Could this suggest a deeper systemic irritation—perhaps from a substance I once applied to these very tissues—rather than a localized growth requiring excision?“

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TEASER Summary Rating: 2

  • Evidence supporting CIMDL: The summary mentions nasal crusting and foul-smelling discharge, which could align with symptoms of CIMDL. However, these are also common in other conditions.
  • Missing/conflicting information: There is no mention of any progressive nasal/oral/facial damage, palate problems, facial deformities, or secondary symptoms like fever or weight loss that are characteristic of CIMDL. The primary diagnosis focuses on atrophic rhinitis, not CIMDL.

MAIN Summary Rating: 3

  • Evidence supporting CIMDL: The mention of chronic nasal irritation potentially from substances like cocaine provides some alignment with CIMDL. Symptoms like crusting, foul-smelling discharge, and nasal bleeding can be seen in CIMDL cases.
  • Missing/conflicting information: While cocaine use is mentioned historically, the summary does not strongly link to current CIMDL indicators such as progressive midline destructive lesions. Additional characteristics like palate damage, facial deformities, or significant secondary symptoms are not discussed. The focus remains primarily on atrophic rhinitis, with only a slight nod to substance use as a potential factor.

Symptoms Analysis:

  • Physical Examination: Nasal examination reveals crusting and foul-smelling discharge. Potential ulceration noted upon removal.
  • Basic Radiography: Limited value for soft tissue differentiation but can exclude significant bony changes.
  • Bacterial Cultures: Routine cultures may identify common pathogens; however, specificity is limited without modern staining techniques.
  • Limitations: Advanced imaging unavailable, impeding detailed assessment of soft tissue and deeper structures.

Primary Diagnosis:

  • Chronic Atrophic Rhinitis (Ozena):
    • Characterized by nasal crusting, foul odor, and potential bleeding.
    • Pathophysiology involves mucosal atrophy, possibly worsened by chemical irritation.

Differential Diagnosis:

  1. Syphilitic Gumma:
    • Ruled out if Wassermann test negative.
    • Presents with ulcerative lesions; systemic signs expected.
  2. Nasal Tuberculosis:
    • Considered if pulmonary or systemic TB history.
    • Would exhibit chronic granulomatous inflammation, detected through biopsy.
  3. Actinomycosis:
    • Chronic suppurative infection; sulfur granules in discharge.
    • Affects both soft and bony tissues; limited to known Actinomyces presence.

Conclusion:

  • Management: Address potential chemical irritants. Nasal hygiene critical. Consider surgical intervention if conservative measures fail.
  • Further Investigation: Biopsy may assist in excluding neoplastic lesions.

PICHLER TEASER002/040125

The primary diagnosis for the symptoms described is likely atrophic rhinitis, characterized by the presence of crusting and foul-smelling discharge in the nasal cavity. This condition can result from chronic nasal irritation or use of irritating substances, such as cocaine, which Sigmund Freud historically applied. Atrophic rhinitis involves the thinning of the nasal mucosa and can lead to bleeding when crusts are removed. The chronic nature of the symptoms and the temporary relief from treatments align with this diagnosis. Critical red flags include persistent or worsening nasal obstruction, recurrent bleeding, and signs of systemic infection (fever, chills), which would necessitate immediate intervention given the potential for complications like secondary infections or further tissue damage.

Differential diagnoses include 1) Chronic sinusitis, which would be supported by nasal blockage and purulent discharge but generally presents with less crusting and more sinus tenderness than atrophic rhinitis. 2) Nasal vestibulitis, characterized by localized infection and inflammation at the nasal entrance, often associated with pain and swelling, distinguishing it from the more diffuse presentation of atrophic rhinitis. 3) Wegener’s granulomatosis (granulomatosis with polyangiitis), a systemic condition that can cause crusting nasal lesions and bleeding; however, it would also likely present with systemic symptoms such as kidney involvement or generalized malaise, which are not indicated in this case. Each alternative diagnosis warrants further investigation through imaging and laboratory tests to confirm or rule out the underlying etiology.

Termin vereinbaren

Ordination Dr. Michael Truppe
Albertgasse 3/6 1080 Wien

Telefon 01 408 95 00 66
Email ordination@smile.wien

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